I-TOSKANI yazalelwa e-Barcelona, ​​eSpain ngo-1953, isekelwe emlandweni wocwaningo lwesayensi lomndeni wezokwelapha oseneminyaka eyikhulu ubudala. Ngeminyaka engama-72 yokutshalwa kwemboni ngokujulile, isikhule yaba uhlobo lomkhiqizo wobuhle bezokwelapha kanye nezimonyo oluqoshwe ku-Atlas of Aesthetic Mesotherapy, incwadi egunyaziwe yodokotela besikhumba emhlabeni wonke.
Ngokugxila emsebenzini walo oyinhloko wokulwa nokuguga kwesayensi, umkhiqizo wakhe isixazululo esihlanganisiwe esingu-360° esihlanganisa isikhumba sekhanda nokunakekelwa kobuso. Kuze kube manje, ilethe imikhiqizo eqondiwe kanye nezinsizakalo ezichwepheshile emitholampilo yochwepheshe yesikhumba engaphezu kuka-15,000 emazweni nasezifundeni ezingaphezu kuka-75 emhlabeni jikelele, ibeka ibhentshimakhi entsha yochwepheshe embonini yobuhle bezokwelapha enamazinga ekhwalithi yezinga lezemithi.